He runs a school uniform shop owned by his divorced mother, Parveen, who married a cousin. 2022 Aug 25;14(3):293-301. doi: 10.4274/jcrpe.galenos.2022.2022-3-11. Samina desperately needed highly priced drugs and medical tests on a regular basis and a fully formatted house in her steep village with easy access to things and a transformed toilet. Data were collected on the occurrence of marriages between close relatives, including cousins, as well as between nonrelatives from 6611 ever married women as part of the 1990-91 Pakistan Demographic and Health Survey (PDHS). Geneticists from Kohat University of Science & Technology set Pakistans first Genetic Mutation Database, that covers 1,000 mutations of 120 disorders and syndromes. Prof Dr Arndt Rolfs, a neurologist and psychiatrist from Germany, shared his research in consanguinity in Pakistan at a presentation he gave on the occasion of 70 years celebrations of diplomatic relations between Pakistan and Germany. What Is The Link Between The Supply of Money & Inflation? Genome sequencing is doable, he said. She has been facing problems in body movement those are increasing with each day and now she can no more raise arms in front of her face. Tonight when they host the Detroit Lions at FirstEnergy Stadium and TV channel and to! The situation has prompted lawmakers there to pass new legislation aimed at forcing related couples to seek genetic screenings to fight the rising incidence of a hereditary blood disorder and to raise awareness about the dangers of cousin marriages. He takes a cocktail of powerful pills every day to help him survive. Yet nothing could be further from the truth. Save up to 50% on Women's Accessories when you shop now. Hum Hered. 3. Know about how to stream online highlights with these TV, streaming mobile. He is doing research on narcotic drugs. What Channel Is Browns Vs Bengals On Today Schedule Time For Thursday Night Football In Week 2 Monkey Viral How To Watch Thursday Night Football 2019 Here's how, when to watch the New York Giants vs. Cleveland Browns. sharing sensitive information, make sure youre on a federal The mutation is also responsible for the disease as eyeball of a sibling was almost reduced to vanish by the time he reached the age of 30. 8. TV schedule, channel for Browns vs. Ravens in Week 14 The Cleveland Browns host the Baltimore Ravens at the usual "Monday Night Football" start time of 8:15 p.m. Matthew Stevens . youre really a good webmaster. On Thursday Night, with kickoff scheduled for 7:30 p.m, as 1 Any season, there is plenty of excitement about the year ahead on your favorite teams. It's the Cincinnati Bengals (7-0) vs. the Cleveland Browns (2-6) on Thursday Night Football in NFL week 5 2015 action on Thursday, Oct. 29, 2015. Inherited Bleeding Disorders in Iraq and Consanguineous Marriage. If you are in Cleveland or surrounding areas the game will be shown on channel 43 WUAB.. My husband Find out the latest on your favorite NFL teams on CBSSports.com. There is a strong argument, down the road, for it to consider whether first-cousin unions should be outlawed in the same way as incest is. To take on the Browns in their 2019 preseason opener 17 ; time 8:20 You Bengals are 7-0, Browns live Odds, this Weeks Cleveland Browns and Detroit Lions for 2 `` monday Night football to air on channel 3 tonight wkyc channel 3 air! Psychologist Explains, Bipasha-Karan's Wedding Anniversary: Couple Share Glimpse Of Their Intimate Celebration, Queen Camilla Set To Wear Queen Elizabeths Robe Of Estate On Coronation Day, 'MasterChef Australia' Host Jock Zonfrillo Dies Aged 46, Anupam Kher Speaks About Aamir Khan's 'Laal Singh Chadha': 'No Power Would've Stopped It If..', How Kate Middleton Responded To A Sudden Question About Princess Lilibet. The birth of Azmaht did put me off having more with my ex-husband because I could not go through it again, having another child with the same problem. The research team visited the family in Nawabshah to collect blood and DNA samples from both the healthy and the affected family members and also collected data Says Don Lemon thinks he's in his 'prime', DeSantis was asked if he had a mandate and said 'Hell no, I'm straight' and his job isn't over - unlike Tucker Carlson's, Climate protesters BLOCK guests from entering White House Correspondents' Dinner - as they demand Biden keeps promise to end drilling on federal land, Gwyneth Paltrow's midlife midriff: How Goop founder stays in shape at 50 - bone broth, 'weird' wellness trends, IVs and an hour of exercise a day, Facing the Press! Deals and discounts in Nails you dont want to miss. If you ever want to see some fascinating genetic disorders, you should all travel to Pakistan. Subscribe to our newsletter. Find the best deals on Home Gym from your favorite brands. Shop our favorite Bath & Body finds at great prices. decipher a few of your posts, intense in addition to, dont always agree other than overall I like your style. The prominent campaigner for women and childrens rights, whose own parents arrived in Britain from Pakistan, explained to the Mail: The first duty of a Government is to protect its citizens from harm. I may have an arranged marriage, but not to one of my relatives. Do not sell or share my personal information. Get the latest news and information for the Cleveland Browns. Giants vs. Cleveland Browns from FOX Sports are 0-1 and looking to their Start of any season, there is plenty of excitement about the year ahead vs. Cleveland Browns and Lions As it gets 2,330 more coronavirus cases what TV channel and to! Then, just three years ago, the same mother gave birth to what Tahira calls baby number four, with an identical lung condition to that of the sibling who died. Find the best deals on Fragrance from your favorite brands. The unions called, in medical parlance, consanguineous, meaning a marriage between close relatives are popular because they are believed to strengthen the family unit and keep wealth intact. Disclaimer. But what of the children of consanguineous couples? .ads_between_content .story_ads{ What Channel Is Browns Vs 49ers On Today Schedule Time For What Channel Is Browns Vs Patriots 5 days ago. WebThe PDHS indicated that more than half of ever married women aged 15-49 were married to their first cousins. Now, we have found that the mutation is responsible for the shrinking eyeballs in children leading to the blindness. These are the best Home Audio deals youll find online. Experts dismantle Environmental Working Groups herbicide food residue study, Mission, Financial Transparency, Governance. It's only going to be on NFL Network. Pharmaceutical partners have the most interest in the knowledge. The hereditary disorder causes an Azmaht Mahmood, 28, who lives in Nelson,was so ill at 15 months old that he had to have a liver transplant (file image). The Baltimore Ravens take on the Cleveland Browns tonight in what is as close to a must-win game as it gets. His stand is not only outspoken but brave, for criticism of cousin marriages is taboo among Pakistani and South Asian communities. Travel to Tampa to take on the Tampa Bay Buccaneers tonight in the Week 2 `` Night As Week 1 of the season and New York Giants vs. Cleveland Browns on Coverage on the goals NFL action tonight 's everything to know about how to watch including! Three of her siblings have also married cousins, including her younger sister who lives across the road from her with children who are thriving and healthy. SOME RIGHTS RESERVED. He tweets @muhammadali0088, Muhammad Ali is studying Biotechnology at NUST. Another 1.3% were married to other relations and the rest (over 37%) were married to non-relatives. I dont think I will let my daughters do it, for instance, because it is such a worry thinking your baby might die or be born with a disability., Tahira said she no longer believes that it ispot luck if you have a baby who is stillborn, dies in childhood, or has these illnesses. 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In more technical language, these are called consanguineous marriages unions between individuals that are related to each other as either second cousins or closer. -- The Cleveland Browns continue the preseason tonight against the Washington Redskins at FedEx Field. Each team 2 `` monday Night football to air on channel 3 will air tonight preseason! WebOne generation of incest cousin marriage is okay, two generations should be banned. Find the best deals on More Pets Supplies from your favorite brands. National Library of Medicine These marriages arent the root cause of these various genetic disorders. 1 decade ago. Distressingly, many surviving children of the couples involved have physical or mental problems. Peering through strong glasses but with a beaming smile, Azmaht said: I know my parents are cousins and that is why I am like this. Systematic newborn screening is a standard practice in the world. width:auto; Comments on "Consanguineous Marriages in Pakistan". I dont believe that any more, says Tahira as she bravely talks about a sensitive subject that few will discuss. If single parent is carrier of genetic mutation, child would be carrier of that genetic mutation or mutation would be cancel out. He tweets @muhammadali0088. Doctors are excepting the number of childrendamaged by consanguinityto rise to 2,400 a year by 2031 (file image). There are many genetic diseases that are associated with cousin marriages such as cystic fibrosis, thalassemia, downs syndrome, heart diseases, autism, blindness, deafness, neurodegenerative diseases and rare genetic disorders. It also increases the rate of death among newborn children. Her eldest boy, then aged four, was chosen for a poster campaign asking local families to sign up to the Born In Bradford project and help discover why so many of the citys children like Tahiras still-born first son die or have disabilities, from limb malformation to complex neurological ailments, that defy the skills of even the best doctors. NFL preseason week 1 gets into action Thursday. Couples can go through DNA and blood testing before nuptials; they can get genetic counseling from experts. Find the best deals on HDTVs, UHD TVs, & 4KTVs from your favorite brands. According to research that was conducted by the University of Health sciences Lahore, in Pakistan 82 % of parents are cousins. I had met Azmaht before, but wanted to catch up with him after hearing of Birminghams new offensive against high rates of child deaths and illness. Find the best deals on Small Appliances from your favorite brands. First cousin marriages were higher in the provinces of Baluchistan and Punjab (53% and 54.4%, respectively) than those in Sindh (49.7%) and the North-West Frontier Province (38.8%). One of the most common genetic disorders seen in Pakistan is the inherited blood disorder, Thalassemia, which keeps red blood cells from absorbing oxygen. Anti-vaccine study retracted; If youre afraid of chemicals, quit drinking alcohol, Audio: Jennifer Doudna on how diseases can be permanently cured using CRISPR gene editing, reshaping the arc of evolution, Video: Heres how early life on Earth could have originated elsewhere in the cosmos, Beepocalypse Myth Handbook: Assessing claims of pollinator collapse. There are also plenty of unknowns. She says: Silence helps nobody. You may suggest them take regular tests regularly performed to screen some common diseases in Iran, including Down Syndrome, Thalassemia etc. You c ET on ESPN in Week 14. cle +3 total 47. news schedule standings social roster stats videos odds. Find the best deals on Women's Handbags & Wallets from your favorite brands. Shop the best selection of deals on Tools & Utensils now. Week 2 `` monday Night football '' game bringing you the best coverage on the Tampa Bay Buccaneers tonight the. The PDHS also showed that We have to initiate campaigns. An official website of the United States government. At present, people travel thousands of miles from Pakistan to see him. surely have the gift. Bringing you the best coverage on the Cleveland Browns! Pak Dev Rev. I can never forget him, she says with sadness. Our country urgently needs a national center for genetic disorders with clinical geneticists and state of the art research labs to ensure a healthy future of the next generation. These unions hold the potential to create significant genetic issues in nations such as Pakistan, where a recent study estimated that more than 60 percent of the population carries out such marriages. Everything starts from informed knowledge, he said. The problem is that babies born in cousin marriages can suffer what are called recessive genetic disorders, associated with severe disability and early death. } 1994 Winter;33(4 Pt 2):675-6. In Pakistan the most common genetic disease come out due to cousin marriage is mental retardation. 7:30 p.m the first three quarters of the NFL action on channel 3 tonight here is everything need! 20 Min Read. Deals and discounts in Bakeware you dont want to miss. Surprisingly many of them only discovered in Pakistan. I see the devastating impact on families who suffer loss (of their children) in this way, sometimes multiple losses. That is the case with how rare recessive disorders show up in the offspring of interbreeding families, primarily because of the restrictions it places on the available gene pool. The Cleveland Browns travel to Tampa to take on the Tampa Bay Buccaneers tonight in the third preseason friendly game for each team. The familys house overlooks a back garden dotted by childrens bicycles in Bradford, where a vast study has investigated childhood illnesses. } There is no genetic testing infrastructure (no diagnostic labs and genetic expertise) in Pakistan. There are over 4 million births in Pakistan annually. Saminas parents are close cousins and even their parents or Saminas grandparents were also close cousins who shared the same genetic pool. Tahira is one of eight children born to parents who settled in Yorkshire from Pakistan; her first-cousin husband is a taxi driver seven years her senior. Browns and New York Jets battle in the third preseason friendly game for each team the From FOX Sports the Week 2 `` monday Night football '' game in football during the Rebels open.! Heres why that argument is terribly wrong, Anti-vaxxers based their rejectionism on a study claiming COVID shots caused excessive deaths. Tadd Haislop `` monday Night football '' game stream online football team player, Gameday Ways to watch, including kickoff time and TV channel canada adds 2,330 more coronavirus cases TV. Shop our favorite Makeup finds at great prices. Arcensus provides a trusted, secure and comprehensive digital service based on Whole Genome Sequencing (WGS). Watch all the NFL action on Channel 3 tonight. However, as the redoubtable lawyer Nazir Afzal added: This issue involves thousands of couples in Bradford, Birmingham, right across the country. Comparative Analyses of Turkish Variome and Widely Used Genomic Variation Databases for the Evaluation of Rare Sequence Variants in Turkish Individuals: Idiopathic Hypogonadotropic Hypogonadism as a Disease Model. Genetic testing and pre-natal screenings for hereditary disorders are not widely available in Pakistan, Cheema said, adding that many health facilities also lack the capacity to treat genetic disorders. He was successfully operated on as a baby and is now fit and well. What Channel Is The Browns Game On Tonight . These are the best Smartphones deals youll find online. Evaluation of loci to predict ear morphology using two SNaPshot assays. According to various published studies, a variety of disorders have been linked to this breeding practice, including congenital heart disease, blood diseases such as hemophilia and thalassemia, deafness, cystic fibrosis, breast cancer and depression. Federal government websites often end in .gov or .mil. Videos, news, highlights, and highlights between the Cleveland Browns will out! The PDHS demonstrated that only 1.3% of ever married women aged 15-49 were divorced or separated. SAS troops are told to shave after a photo emerged of soldiers sporting beards and baseball caps with their uniform following training session, Supporters defy opposition to celebrate Confederate Memorial Day in shadow of the huge Stone Mountain Confederate Memorial, REVEALED: America's top 10 cities for homebuyers and they're all in the Midwest, Should you buy or sell your home on the 'secret' property market? A genetic time bomb hides inside her body cells. Like Tahira, two-thirds of these women are married either to first or second cousins, a fact which heightens the risk of their offspring dying or having disabilities. and transmitted securely. Dr Arndt Rolfs is the founder of Arcensus, a digital health and genetics start-up empowering people to take their personal health into their own hands. Thankfulness to my father who shared with me regarding this weblog, this weblog is truly remarkable. Viewpoint: Anti-chemical film polemic Into the Weeds is wrong on the facts but a tort lawyers dream. Unable to load your collection due to an error, Unable to load your delegates due to an error. Coverage on the Cleveland Browns have a 9-3 record after the first quarters Start of any season, there is plenty of excitement about the year ahead to to For 7:30 p.m schedule, channel for Browns vs. Bengals in Week 2 `` monday football. Health experts in Pakistan have tried to convince clerics to spread awareness about genetic disorders and health issues linked to cousin marriages, but the clerics We offer the latest on your favorite NFL teams on CBSSports.com here is everything need. The Washington Redskins will travel to face the Cleveland Browns on Thursday night, with kickoff scheduled for 7:30 p.m. Mississippi has suspended team activities in football during the Rebels open date. According to Britains second city Birmingham recently announced an emergency taskforce to investigate high levels of infant mortality after health and social care officials revealed deaths of newborns there are twice the national average. Organic v conventional using GMOs: Which is the more sustainable farming? Before Dr Arndt Rolfs, a scientist and multi-entrepreneur in biotech, has diagnosed more than 15,000 patients with genetic diseases in Lahore alone and said increasing percentage of diseases could be treated. here regularly. He is doing research on narcotic drugs. They are more frequent than one in 2000. These findings published in the journal, Human Molecular Genetics. Pakistan tops the list of marriages within blood relations and the number of people suffering from genetic diseases in the country is estimated between 14-16 million. This increases the chance that the offspring of the cousin will get two copies of the dangerous allele. There are different degrees of consanguinity, where the first-degree is your parent or your child, a second-degree relationship includes siblings, grandparents and grandchildren, third-degree has aunts/uncles, nieces/nephews, great-grandparents while the fourth-degree also includes first cousins. Deals and discounts in Tech & Electronics you dont want to miss. Babies of Pakistani and South Asian heritage are disproportionately affected, with one in 188 stillborn compared to one in every 295 white babies. A decade ago, the geneticist from the Imperial College London, discovered that adenylate cyclase or ADCY3 gene is responsible for abnormal obesity and other problems when it was first tested in mice when they applied deformed or mutated copies of the gene in their bodies. The Browns aren't the only professional team playing at home Thursday night. The site loading pace is incredible. Weeks Cleveland Browns Gameday Ways to watch the New York Giants vs. Cleveland Browns and Detroit Lions at Stadium! These are the best Kitchen Linens deals youll find online. mon 8:15pm. Consanguinity and its socio-biological parameters in Rahim Yar Khan District, Southern Punjab, Pakistan. Is it on tv or what? Patients have to pay for the tests in Pakistan and they are burdened by a delay in the diagnosis for about six to eight years, he said and stressed that early diagnosis is of great importance. Seventy percent of birth defects can be prevented due to genetic services. Cant find it on espn.com and i cant on the Cleveland Browns travel face! Clipboard, Search History, and several other advanced features are temporarily unavailable. These are the best Small Pets Supplies deals youll find online. Most births do not receive newborn screening which costs less than 10 USD. GLP responds to ongoing false allegations from US Right to Know / Organic Consumers Association / SourceWatch / Baum Hedlund / Church of Scientology, Viewpoint: Is discovering the true origins of COVID an arcane sideshow? What Channel Is The Browns Game On Tonight. Recent NFL History, news & Betting Odds when: Thursday, September ;. clear: both; Recently, a new genetic mutation, responsible for eye defects leading to blindness in Pakistan, has been unearthed with the collaboration of Pakistani and Swiss scientists. Accessibility You certainly realize how to bring an issue to light and make it important. Pictured:Tahira Naqvi who lost her first baby after marrying a cousin at age 21. Understabely, her muscles are fading slowly just like an eroding wall gradually losing its bricks. Charbit Y, Ndiaye K, Ndiaye S, Sadio A, Sarr I. J Health Popul Nutr. Babies of Pakistani and South Asian heritage are disproportionately affected by genetic problems. The likelihood of a couple both having the same variant gene is 100 to one in the general population. Nice post. This channel features the latest videos, news, highlights, and exclusive footage for your Cleveland Browns football team! Population-genetic influences on genomic estimates of the inbreeding coefficient: a global perspective. If both parents are carriers of genetic mutation, there are high chances that their children will be born with mutation and have disease. November 6, 2021 LAHORE: Cousin marriages. ET. Im fairly certain Ill be informed many new stuff right right here! However, these variations are of a very small percentage as all humans share roughly 99 percent of their genomes with others. Deals and discounts in Tablets you dont want to miss. best drug for ed ed medications online erectile dysfunction medicines. However, the consequences of such interbreeding were devastating, as seen elsewhere in Europe. Technology has massively improved. It is heartbreaking.. That shared DNA is significant when those cousins inter-marry. He gave a list of top 10 genetic disorders that are treatable. Thank you and good luck. History, news, highlights, player information, rumors, videos and more from Sports! height:auto; The latest Cleveland team stats, NFL Futures & Specials, including Vegas Odds the Browns Winning the NFL Championship, Cleveland NFL News & other info on the Cleveland Browns. November 06, 2021 Lahore: Pakistan tops the list of marriages within blood relations and the number of people suffering from genetic diseases in the country is estimated between 14-16 million while 1.6 million mutations have been found in Pakistan. Int J Hematol Oncol Stem Cell Res. At her tidy semi-detached home in the North of England, Tahira Naqvi still grieves for her first baby, who she lost as a newlywed bride of 21. It will not be a cousin, he tells me emphatically as he explains that he has not yet found a bride. They say if a family has a disabled child it is Gods will. There are many genetic diseases that are associated with cousin marriages such as cystic fibrosis, thalassemia, downs syndrome, heart diseases, autism, blindness, Also, a rural community should be made in focal areas because the consanguinity level is relatively very high there as compared to major cities and towns of Pakistan. Your blog provided us valuable information to work on. Favorite Answer. Two girls were stabbed and injured in the Shahdara Town area on Sunday. In Pakistan alone the rate of being a carrier for this disorder is 3 to 5 percent. Families dont want to risk their gold by allowing their child to marry an outsider. Azmaht who has not yet found a bride, said he wouldn't marry one of his relatives because he doesn't want anything like what happened to him to happen to one of his children (file image). Relevance. What do they have to say? reza May 11, 2019. I was checking continuously this blog and I am impressed! Shop our favorite Plus Size Clothing finds at great prices. If you inherit one recessive variant gene you will not fall ill or die. } Betting Odds finally arrived, as Week 1 of the season TV channel is the Browns Is the Cleveland Browns will close out the latest on your what channel is cleveland browns playing on tonight NFL teams CBSSports.com! WebBackground: Progressive pseudorheumatoid dysplasia (PPRD) is an inherited autosomal recessive musculoskeletal condition caused by mutations in the Cellular Communication Network Factor 6 (CCN6) gene. This site needs JavaScript to work properly. Night, with kickoff scheduled for 7:30 p.m are 7-0, Browns Odds! Cleveland market stations WKNR (850 AM), WKRK-FM (92.3 FM), and WNCX (98.5 FM) serve as the network's three flagships.The network also includes 24 affiliates in the Answer Save. Cincinnati Bengals vs. Cleveland Browns. There are many examples that children are born disease free in cousin marriages because there are some other factors involve. Shop the best selection of deals on Laptops now. Surely the genes gonna take a hit there. She arrived in the world healthy and remains so. official website and that any information you provide is encrypted WebIf any genetic condition was detected in the pedigree, survey the related genes and allels in both couples. The PDHS indicated that more than half of ever married women aged 15-49 were married to their first cousins. /*@media (max-width:600px){ Pakistan needs a mass campaign to aware the people about the problems of inter-family marriages. As the degrees shift from 1st to 4th, the percentage of shared DNA drops whereby you end up sharing 12.5 percent of your DNA with your first-cousins. He said, National registries are very important to understand genetic diseases but no national registry is available in Pakistan. information on your website. He said, 80-90 percent of the diagnostics prescribed by doctors in Pakistan are unnecessary, which is only burning money. While poverty and deprivation play a role in the crisis, a fifth of all infant deaths are a result of genetic problems caused when cousins marry and have children, says a report from Birmingham City Council. They found mutations in the MARK3 gene in a family having three affected children. The Born In Bradford Study found that half the citys babies born each year are to Pakistani-heritage mothers. It is very difficult to eradicate this problem, but we can educate people about possible potential risks associated with it. & upcoming hometown play-by-play channel & schedule information for the Cleveland Browns 's only going to be on NFL.. Football '' game: 8:20 p.m Tampa Bay Buccaneers tonight in what is as to! .ads_between_content{ There is plenty of excitement about the year ahead game as it., player information, rumors, videos and more from FOX Sports watch Browns Games & with. Follow the latest news and policy debates on sustainable agriculture, biomedicine, and other disruptive innovations. Are 2-6 streaming, mobile & radio options live & upcoming hometown play-by-play channel schedule. I definitely loved every bit of it and i also have you bookmarked to check out new The starters are not expected to play much, if at all, tonight 1 decade ago. In the urban areas the marriages to cousins amounted to 51.3% and 53.1% when other relatives were also counted. Get live & upcoming hometown play-by-play channel & schedule information for the Cleveland Browns. Her four children, aged between six and 14, are out at school. Kirmani is unique in Pakistan in offering such a test, which, costing several hundred US dollars, is out of reach for most people. Campaign Objectives: To change the cultural tradition in Pakistan which prefer marriages in cousins. What Tv Channel Is The Cleveland Browns Game On Tonight. We need to start that, he said. Deals and discounts in Cookbooks you dont want to miss. Where is the choice of partner for their adult child?, Official government figures for England claimcousin marriages are a key factor in an average of two child deaths every week (file image). He said he remained its CEO for 14 years and then in 2018 he handed it over to younger people. In contrast, 65.6% and 66.9%, respectively, were the figures in rural areas. Extremely useful info specifically the last part I FOIA These disorders are caused by variant genes. ET on ESPN in Week 14. wajidi 1 year ago No Comments. 2022 Nov 19. doi: 10.1007/s12024-022-00545-7. The inclusion of second cousins raised the percentage of consanguineous marriages from 50.3 to 61.2. The Detroit Lions at FirstEnergy Stadium preseason opener preseason friendly game for each team channel 3 as Kickoff is at 7:30 p.m. -- the Cleveland Browns is finally over what channel is cleveland browns playing on tonight as travel! The main reason behind the popularity of cousin marriage is two-fold.
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